Bone Analysis

For superior bone micro-architecture investigations

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Benefit from insightful visualizations and discover new productivity for your bone image analysis needs…

Pairing robust quantification with limitless extensibility and an unmatched ease-of-use, Dragonfly's Bone Analysis module helps you reach conclusions quickly, accurately, and confidently. With the newly released and previously unavailable option to analyze trabecular anisotropy by orientation, Dragonfly is simply the smartest choice for understanding complex metabolic bone diseases and for helping to develop new therapies and treatments.

Morphometric measurements for superior bone microarchitectural investigations…

Starting from automatic and user-guided isolation of bone from non-bone tissue by means of threshold-based segmentation, Dragonfly's Bone Analysis module can then separately identify cortical and trabecular bone in whole-bone specimens. The calculation of common bone morphometric measurements from these segmented regions then provide quantitative descriptions of bone microarchitecture.

The available measurements for segmented bone, as described by Bouxsein et al. 2010. JBMR 25(7):1468-86, are listed in the tables below.

Global measurements for segmented cortical and trabecular areas

Measurement Abbreviation Unit
Anisotropy (from MIL) -- --
Anisotropy (from SVD) -- --
Bone Volume BV unit3
Total Volume TV unit3
Bone Volume Fraction BV/TV %
Average Cortical Thickness Ct.Th unit
Average Trabecular Thickness Tb.Th unit
Average Trabecular Separation Tb.Sp unit
Average Cortical Area Ct.Ar unit2
Average Marrow Area Ma.Ar unit2
Average Total (Cortical + Marrow) Area Tt.Ar unit2
Average Cortical Area Fraction Ct.Ar/Tt.Ar %
Periosteal Surface (3D Evaluation) Ps.S3D unit2
Endocortical Surface (3D Evaluation) Ec.S3D unit2
Average Periosteal Perimeter Ps.Pm unit
Average Endocortical Perimeter Ec.Pm unit

Per slice (any oblique) measurements for segmented cortical and trabecular areas

Measurement Abbreviation Unit
Moment of Inertia Anteroposterior Axis Iap unit4
Moment of Inertia Mediolateral Axis Iml unit4
Maximum Moment of Inertia Imax unit4
Minimum Moment of Inertia Imin unit4
Polar Moment of Inertia J unit4
Average Cortical Thickness Ct.Th unit
Average Trabecular Thickness Tb.Th unit
Average Trabecular Separation Tb.Sp unit
Periosteal Perimeter Ps.Pm unit
Endocortical Perimeter Ec.Pm unit

In adition to the above indices, the Bone Analysis module provides mapping of anisotropy as follows:

  • Map of local anisotropy
  • Field of local anisotropy orientation

Bone Analysis Datasheet

Bone Analysis results…

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